Natasha Henstridge and Costas Mandylor are about to have a rough “night” in the official trailer to the upcoming thriller Night of the Sicario.

While transporting the family of a key witness in a federal trial against the cartel, DEA agents are ambushed in a fatal shootout. Now the survivors, including the witness’ young daughter, must take refuge in a nearby home as the ruthless sicarios hunt them down. With danger at every corner and a violent hurricane wiping out any chance of outside help, they must play a deadly game of cat and mouse with the cartel to live through the night.

Manny Perez co-stars in the Joth Riggs-directed film, from a script by Ernesto Melara and Matthew Eason.

Night of the Sicario is coming to select theaters on April 16 followed by an On Demand/Digital release date on April 20 from Saban Films.